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The advance application of Copper Tripeptide (CAS 89030-95-5)

Copper Tripeptide-1 (GHK-Cu, CAS 89030-95-5) is a multifunctional bioactive peptide-copper complex with two primary domains of application, driven by its role as a cellular signaling molecule that promotes tissue repair and modulates gene expression.

Core Applications

1. Cosmetic & Skincare (Primary Market)

  • Anti-Aging: Stimulates synthesis of collagen, elastin, and glycosaminoglycans (e.g., hyaluronic acid), reducing wrinkles and improving skin firmness and hydration.
  • Antioxidant: Activates the endogenous antioxidant enzyme superoxide dismutase (SOD), protecting skin from oxidative stress.
  • Repair & Healing: Accelerates wound healing, reduces scarring, and improves skin barrier function.
  • Anti-Inflammatory: Calms skin, reduces redness, and soothes irritation.
  • Hair Growth: Stimulates hair follicle cells, used in scalp treatments and hair loss serums.

2. Biomedical & Therapeutic

  • Wound Healing: Enhances healing of chronic wounds (diabetic ulcers, burns) by attracting repair cells and modulating inflammation.
  • Tissue Regeneration: Investigated for nerve repair, bone regeneration, and internal organ healing due to its ability to shift gene activity toward regenerative states.
  • Post-Surgical Care: Used to minimize scarring and improve recovery.

Key Mechanisms

  • Gene Modulation: Influences over 4,000 genes involved in tissue repair, inflammation, and antioxidant defense.
  • Copper Delivery: Provides bioavailable copper as an essential cofactor for key enzymatic processes.
  • Chemotaxis: Acts as a signal to recruit immune cells (macrophages) to sites of damage.

Typical Use in Formulations

  • Concentration: 0.5% to 3% in serums, creams, gels, and masks.
  • Synergies: Often combined with other peptides (e.g., Matrixyl), antioxidants (Vitamin C, E), and hyaluronic acid.
  • Appearance: Characteristic blue color due to the copper complex.
  • Stability: Requires protection from extreme pH, heat, and certain preservatives.

Safety & Notes

  • Generally well-tolerated topically; rare irritation.
  • Cosmetic-grade use is predominant; therapeutic wound-care applications are more regulated.
  • Efficacy depends on formulation quality and skin penetration.

In summary, Copper Tripeptide is a versatile active ingredient whose dominant application is in high-performance anti-aging and repair skincare, with significant potential in advanced wound care and regenerative medicine.

Copper tripeptide CAS 89030-95-5

Post time: Jan-02-2026