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Ethylhydrogenmalonate CAS:1071-46-1

Ethylhydrogenmalonate, or diethyl malonate, is a colorless liquid with a fruity odor and the chemical formula C5H8O4. It is commonly used as a reagent in organic synthesis due to its versatile nature.

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Application and Effect:

Ethylhydrogenmalonate has various important applications in organic chemistry. It is widely used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Due to its ability to undergo reactions such as esterification, alkylation, and condensation, it serves as a valuable intermediate for the production of numerous compounds. One of its key uses is as a Michael donor in the Michael addition reaction, which is a fundamental transformation in organic synthesis. Additionally, it is utilized in the preparation of barbiturates, vitamin B1, and various flavoring agents. Its ability to undergo decarboxylation reactions makes it an essential component in the formation of substituted acetic acid derivatives. Moreover, diethyl malonate serves as a precursor in the synthesis of pyrazoles, which are important heterocyclic compounds with diverse biological activities. Its versatility and reactivity make it an indispensable component in the construction of complex organic molecules, thereby contributing to advancements in pharmaceuticals, materials science, and agrochemicals. Overall, ethylhydrogenmalonate plays a crucial role in the development of numerous functional compounds and materials that benefit various industries and scientific research.

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Composition C5H8O4
Assay 99%
Appearance white powder
CAS No.  1071-46-1
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.


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