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Fidaxomicin CAS:873857-62-6

Fidaxomicin is a narrow-spectrum antibiotic medication used to treat Clostridioides difficile infection (CDI), commonly known as C. difficile-associated diarrhea. It belongs to the class of macrocyclic antibiotics and works by inhibiting the growth of C. difficile bacteria in the gastrointestinal tract. Fidaxomicin is specifically designed to target this bacterium while preserving the normal gut flora, reducing the risk of recurrent infections.

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Application and Effect:

Fidaxomicin is primarily indicated for the treatment of Clostridioides difficile infection, particularly in cases of moderate to severe CDI where traditional therapies have been less effective or associated with high recurrence rates. It is administered orally in tablet form, allowing targeted delivery to the site of infection in the colon. The unique mechanism of action of fidaxomicin involves inhibiting bacterial RNA polymerase, disrupting protein synthesis in C. difficile cells. By targeting this specific pathogen without affecting the beneficial gut microbiota, fidaxomicin helps restore microbial balance in the colon and reduce the risk of recurrent CDI episodes. Patients with confirmed or suspected C. difficile infection are typically prescribed fidaxomicin for a specified duration depending on the severity of the infection. Adherence to the prescribed dosage and regimen is critical to achieving optimal clinical outcomes and minimizing the risk of recurrence. Common side effects may include nausea, abdominal pain, and gastrointestinal disturbances; however, fidaxomicin generally exhibits good tolerability compared to other CDI treatments. Regular monitoring during treatment and follow-up evaluations post-therapy are essential to assess response, monitor for adverse reactions, and prevent relapse of C. difficile infection. Healthcare providers play a vital role in guiding the appropriate use of fidaxomicin to effectively manage CDI and promote patient recovery.

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Additional Information:

Composition C52H74Cl2O18
Assay 99%
Appearance white powder
CAS No.  873857-62-6
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.


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