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S-Butyrylthiocholine iodide CAS:1866-16-6

S-Butyrylthiocholine iodide is a chemical compound commonly used in biochemical and enzymatic assays. It is a substrate for the enzyme butyrylcholinesterase (BChE) and is used to measure its activity.

When S-Butyrylthiocholine iodide is hydrolyzed by BChE, it produces thiocholine and butyric acid as products. The release of thiocholine can be measured using a spectrophotometric or fluorometric assay, allowing quantification of BChE activity.

S-Butyrylthiocholine iodide is often used in clinical and research settings to evaluate the activity of BChE in samples such as blood plasma or tissues. It can be used to assess the enzymatic function of BChE and its potential role in various biological processes, as well as in the diagnosis and monitoring of certain medical conditions.


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Application and Effect

Enzymatic Assays: BTCI is widely used in experimental setups to determine BChE activity. It serves as a substrate that, when cleaved by BChE, produces a measurable reaction product. The generated thiocholine can be quantified using spectrophotometric or fluorometric methods, providing information about the BChE activity levels.

Clinical and Diagnostic Applications: BChE activity measurement using BTCI has clinical significance, particularly in the diagnosis and monitoring of various medical conditions. Abnormal BChE levels have been linked to certain diseases, including liver and kidney disorders, neurodegenerative disorders (such as Alzheimer's disease), and exposure to certain toxins. Assessing BChE activity using BTCI can aid in the detection and management of these conditions.

Pharmacological Studies: BTCI and BChE are also relevant in pharmacological research and development. BChE is involved in the metabolism of certain drugs, including muscle relaxants and local anesthetics. By studying the effect of drugs on BChE activity using BTCI as a substrate, researchers can gain insights into drug metabolism, potential drug interactions, and the development of novel therapeutic agents.

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Additional Information:

Composition C9H20INOS
Assay 99%
Appearance White powder
CAS No. 1866-16-6
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.


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