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Tazobactam sodium salt CAS:89785-84-2

Tazobactam sodium salt is a water-soluble derivative of tazobactam, a beta-lactamase inhibitor commonly used in combination with beta-lactam antibiotics such as piperacillin. It enhances the efficacy of beta-lactam antibiotics by preventing bacterial resistance mediated by beta-lactamases, enzymes that degrade beta-lactam antibiotics. Tazobactam sodium salt is particularly effective against gram-negative bacteria that produce beta-lactamases, restoring the activity of beta-lactam antibiotics against these resistant strains.

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Application and Effect:

Tazobactam sodium salt, in combination with piperacillin, is used in the treatment of various bacterial infections, including complicated urinary tract infections, intra-abdominal infections, pneumonia, and skin and soft tissue infections. This combination therapy, known as piperacillin-tazobactam, provides broad-spectrum coverage against gram-negative and some gram-positive bacteria. The dosage and duration of piperacillin-tazobactam therapy depend on the specific infection being treated, the patient's renal function, and other individual factors. It is administered intravenously, either intermittently or continuously, under medical supervision. Patients should be aware of potential side effects associated with piperacillin-tazobactam therapy, including gastrointestinal disturbances, allergic reactions, and rare but serious adverse effects like pseudomembranous colitis. Monitoring for adverse reactions during treatment and promptly reporting any unusual symptoms to healthcare providers are important precautions for safe and effective use of tazobactam sodium salt in combination with piperacillin. Consulting with healthcare professionals for personalized treatment recommendations and guidance on managing side effects is essential for optimal patient care.

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Additional Information:

Composition C10H12N4NaO5S
Assay 99%
Appearance white powder
CAS No.  89785-84-2
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.


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